Health and wellness brand Naples Soap Co. entered into manufacturing agreements to produce proprietary 3D stem cell formulas utilizing technology developed by NASA for use in new personal care product lines. Company officials said the proprietary complex in development combines 33 different components to nourish the skin, such as different forms of hyaluronic acid, vital nutrients, amino acids and proteins, including collagen and cytokines—growth factors that stimulate cell growth and tissue repair—cultured in a zero-gravity bioreactor. NASA made a leap in cellular science when it discovered that in zero gravity, cells are unrestricted and grow three-dimensionally, much like in the body. The cells reproduce faster, in more abundance and a nutrient-dense manner. To replicate the environment in space, NASA scientists developed a zero-gravity bioreactor tested by astronauts on nine different space missions, resulting in a proprietary method to culture robust 3D stem cells on Earth. In contrast, stem cells grown in standard labs are typically grown in a 2D petri dish setting. Naples Soap will use ingredients generated from 3D stem cells grown in a NASA-designed zero-gravity bioreactor in Florida.